Snes9x - one of the first Super NES emulators out there - is now compatible with Vista. Due to the OpenGL / DirectDraw rendering it uses and Vista's problems regarding the OpenGL standard this was not the case.The older release does function with the Classic interface enabled though. This derivative of the standard Snes9X code base introduces direct3D DX9 as method of accelerated screen drawing and the advantages are an optional bi-linear filter and no problems with Aero on Vista. One disadvantage: the menu doesn't work in full-screen without flickering, so it's disabled for now (ESC now exits full-screen).

Here is a link to to binary and sources of this release. Definitely worth checking out of you want to use Snes9X on a Vista machine with Aero switched on and don't want to use Zsnes - which actually offers a more exact Snes emulation.